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Karl Schenk (December 1, 1823 - July 18, 1895) was a Swiss politician.

He was elected to the Federal Council of Switzerland on December 12, 1863 and died in office 31 years later, on July 18, 1895. As of 2004, he is still the longest-serving member. He was affiliated with the Free Democratic Party of Switzerland. During his office time he held the following departments:
- Department of Home Affairs (1864)
- Political Department (1865)
- Department of Home Affairs (1866 - 1870)
- Political Department (1871)
- Department of Home Affairs (1872)
- Department of Finance (1872)
- Department of Home Affairs (1873)
- Political Department (1874)
- Department of Railway and Trade (1875 - 1877)
- Political Department (1878)
- Department of Home Affairs (1879 - 1884)
- Political Department (1885)
- Department of Home Affairs (1886 - 1895)
Predecessor: Jakob Stämpfli
Successor: Eduard Müller

