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Many makes and models of computers could run, or ran, some version of the CP/M operating system. The following is an alphabetical list of some of those computers:
- MITS Altair 8800
- Amstrad CPC 6128 (and 664)
- Amstrad PCW 8256/8512/9512
- Amust Executive 816
- Apple II (with Microsoft Z80 Softcard)
- Aster CT-80
- Atari ST
- Bigboard
- BBC Micro (with external Z80 module)
- Bondwell
- Commodore 128
- Datamax UV-1R
- DEC Rainbow
- Epson Geneva
- Exidy Sorcerer
- IBM PC
- IMSAI 8080
- Intel MDS-80
- Iotec
- Kaypro
- MCP (128k z80, S-100 bus)
- Applied Technology Microbee (models with >= 56KB RAM)
- Mycron 3
- NEC APC
- Northstar Horizon
- Osborne 1
- Otrona Attache
- Processor Technology Sol-20 (optional)
- Research Machines 380Z
- Research Machines Link 480Z
- Tandy TRS-80
- Xerox 820
- Zenith Z-100
- Zorba
